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Particulate and Spectroscopic Experience
"The only source of knowledge is experience."
- Albert Einstein
Powder Characterization
Powder characterization forms the foundation for traditional solid dosage form pharma, many industrial products, and even sees application in biologics manufacturing. Analytical needs run the gamut from raw material identification, measuring simple particle size distributions of actives and excipients, to deconvolving complex blends of solid powders. Common techniques include:
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Laser Diffraction
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Optical Microscopy
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Polarized Light Microscopy
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Flow Microscopy
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Bulk Raman and FTIR Spectroscopy
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Raman and FTIR Microspectroscopy
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Handheld Raman and FTIR Spectroscopy
Small Molecule
Small molecule pharmaceuticals go back generations - the definition of a mature analytical field. ​ Even so, many applications require specialized experience for optimal results. Particlese has amassed intimate knowledge of these applications including characterization of suspensions, emulsion globule size, particles-in-gel characterization, polymorph discrimination, as well as solid-dosage-form content uniformity. Common techniques include:
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Laser Diffraction
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Optical Microscopy
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Polarized Light Microscopy
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Raman and FTIR Microspectroscopy
Biologics are the new frontier in pharmaceuticals, offering novel therapeutic pathways with attendant delivery modalities. Analytics within the field are rapidly evolving to effect product characterization. Particlese's experience in biologics includes formulated antibodies, adjuvanted vaccines, and newer delivery methods such as lipid nanoparticles (LNPs) and viral vectors, proteinaceous aggregate characterization, stability, and foreign particulate matter characterization. Common techniques include:
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Optical Microscopy
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Flow Microscopy
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Imaging Flow Cytometry
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Raman and FTIR Microspectroscopy
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SEM-EDS
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Dynamic Light Scattering
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Nanoparticle Tracking Analysis
Biologics
Other
Particlese's experience in pharmaceutical analytics can be leveraged outside the realm of applied science. Not only have we directed an analytical laboratory and managed analyst resources, but we've also worked extensively in training, regulatory documentation, business development, and scientific market building. We also have a strong history of high-quality scientific publications, webinars, and conference presentations.
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